CD53 and ECE2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CD53	ECE2
Description		CD53 molecule	endothelin converting enzyme 2
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Golgi Membrane Plasma Membrane Integral Component Of Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Metalloendopeptidase Activity Methyltransferase Activity Metal Ion Binding
	Biological Process	Signal Transduction Positive Regulation Of Myoblast Fusion	G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Protein Processing Peptide Hormone Processing Methylation
Pathways		Neutrophil degranulation	Peptide ligand-binding receptors
Drugs
Diseases
GWAS		Cytomegalovirus antibody response ( 21993531) Obesity-related traits ( 23251661)	Body mass index ( 29273807) Daytime nap ( 33568662) Major depressive disorder ( 22472876) Menarche (age at onset) ( 21102462)
Interacting Genes		80 interacting genes: AIG1 APOD ARL13B ASGR2 ATP6V0C BCL2L13 BIK BTN2A2 C1QL4 CD2 CD302 CD37 CD4 CD9 CLCN7 CLDN19 CLDN7 CLEC7A CNIH1 CNIH2 COL4A5 CREB3L1 CTXN3 CXCL16 CYBC1 ECE2 EFNA5 EMP1 ERG28 FAM209A GET1 GGT1 GIMAP5 GJA8 GPR108 GPR152 GPX8 IFITM3 IGFBP5 IL2 IL4 KIR3DL3 LAT LHFPL5 LPAR3 LSMEM1 MAL MS4A3 MUC1 NKG7 PLN PLP2 PMP22 PSCA RPRM SAR1A SERTM1 SLC35A1 SLC7A14 SMAGP SMIM3 SNORC ST6GAL2 STRIT1 STX2 TMEM128 TMEM140 TMEM218 TMEM229B TMEM237 TMEM60 TMEM86B TMEM97 TRAM1L1 TRARG1 TSPO2 UBIAD1 UPK1B VAMP5 VSTM1	6 interacting genes: CASP10 CD53 CD86 MTNR1A SYNE4 UBC
Entrez ID		963	9718
HPRD ID		01054	09931
Ensembl ID		ENSG00000143119	ENSG00000145194
Uniprot IDs		B4DQB5 P19397	P0DPD6 P0DPD8
PDB IDs		6WVG
Enriched GO Terms of Interacting Partners?
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