GUCA1C and PSORS1C2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GUCA1C	PSORS1C2
Description		guanylate cyclase activator 1C	psoriasis susceptibility 1 candidate 2
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Disc Membrane	Cellular_component Extracellular Region
	Molecular Function	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity	Molecular_function Protein Binding
	Biological Process	Signal Transduction Visual Perception Positive Regulation Of Guanylate Cyclase Activity	Biological_process
Pathways		Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Broad depression or schizophrenia ( 30626913) Clostridioides difficle infection in antibiotics-users ( 33841421) Height ( 28552196 25282103) Hematology traits ( 23263863) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Metabolite levels ( 23823483) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Night sleep phenotypes ( 27126917) Serum uric acid levels ( 30993211) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 21738480)
Interacting Genes		2 interacting genes: HGS PSORS1C2	27 interacting genes: AGR2 AP1B1 AP2B1 BANP CEP70 ERICH2 EVPL GUCA1C HMG20A HOMER3 LHX3 MED20 MEIS3 MYL2 MYL7 NCKIPSD PAX6 PEX19 REL RTRAF SERTAD1 SGTA SGTB TTC23 UBQLN1 UBQLN2 VASP
Entrez ID		9626	170680
HPRD ID		05499	17921
Ensembl ID		ENSG00000138472	ENSG00000204538
Uniprot IDs		O95843	A0A1U9X9A6 Q9UIG4
PDB IDs		2GGZ
Enriched GO Terms of Interacting Partners?
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