H6PD and TNFRSF4

		H6PD	TNFRSF4
Description		hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase	TNF receptor superfamily member 4
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Lumen	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Glucose-6-phosphate Dehydrogenase Activity 6-phosphogluconolactonase Activity Carbohydrate Binding Glucose 1-dehydrogenase (NAD+) Activity Glucose 1-dehydrogenase (NADP+) Activity NADP Binding	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding
	Biological Process	Glucose Metabolic Process Pentose-phosphate Shunt, Oxidative Branch Response To Alcohol Regulation Of Cortisol Biosynthetic Process	Positive Regulation Of Immunoglobulin Production Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell
Pathways			TNFs bind their physiological receptors
Drugs		NADH
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Height ( 25282103 23563607 31562340) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 34021172)	Inflammatory bowel disease ( 23128233)
Interacting Genes		1 interacting genes: TNFRSF4	18 interacting genes: BTG2 DHX38 H6PD LUZP1 MAPK14 MLLT6 NAP1L5 NUFIP2 PRRX1 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5
Entrez ID		9563	7293
HPRD ID		00681	02636
Ensembl ID		ENSG00000049239	ENSG00000186827
Uniprot IDs		O95479	P43489
PDB IDs			1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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