STX8 and KCNMB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STX8	KCNMB1
Description		syntaxin 8	potassium calcium-activated channel subfamily M regulatory beta subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Late Endosome Endoplasmic Reticulum Trans-Golgi Network Cytosol Integral Component Of Plasma Membrane Endomembrane System Integral Component Of Membrane SNARE Complex Late Endosome Membrane Vesicle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome	Plasma Membrane Voltage-gated Potassium Channel Complex Synapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding Ubiquitin Protein Ligase Binding	Calcium-activated Potassium Channel Activity Potassium Channel Regulator Activity
	Biological Process	Intracellular Protein Transport Vesicle Fusion Endosome To Lysosome Transport Early Endosome To Late Endosome Transport Vesicle Docking Cellular Response To Interferon-gamma Regulation Of Protein Localization To Plasma Membrane	Detection Of Calcium Ion Potassium Ion Transport Chemical Synaptic Transmission Aging Vasodilation Cellular Response To Ethanol Cellular Response To Hypoxia Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Bile Acid
Pathways			Ca2+ activated K+ channels cGMP effects Sensory processing of sound by inner hair cells of the cochlea Acetylcholine inhibits contraction of outer hair cells
Drugs			Procaine Miconazole Trimebutine
Diseases
GWAS		Blood protein levels ( 30072576) Borderline personality disorder ( 28632202) Brain morphology (MOSTest) ( 32665545) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)	Acne (severe) ( 24927181) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025)
Interacting Genes		84 interacting genes: ACVR1 AMIGO1 AQP2 ASGR2 BCL2L13 BIK BSND CALM1 CD300E CD79A CERS4 CLDN9 CLN8 COPA CPLX4 CREB3 CREB3L1 DHRS9 DNAH9 EBP ERGIC3 FAM174A FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GORAB GPR151 GPR152 GPR42 GPX8 JAGN1 JSRP1 KCNMB1 LMNA MCEE MCL1 MFF MGST2 MGST3 MMGT1 MS4A3 MTERF3 NAPA NAPG NCR3LG1 NDUFAF1 NDUFAF2 NSF PEX12 PSCA RETREG3 RNASEK SAR1A SCN3B SGPL1 SLC10A6 SLC18A1 SLC22A2 SSMEM1 STAR STMN4 STX1A STX2 STX4 STX5 STX7 TGFBR1 TMED8 TMEM14B TMEM179B TMEM205 TMEM237 TMEM86B TMPPE TMPRSS2 TSPAN12 VAMP5 VPS11 VPS18 VTI1B WDR91	5 interacting genes: CLCA1 EWSR1 KCNMA1 MT-CO1 STX8
Entrez ID		9482	3779
HPRD ID		05012	10358
Ensembl ID		ENSG00000170310	ENSG00000145936
Uniprot IDs		Q9UNK0	Q16558
PDB IDs
Enriched GO Terms of Interacting Partners?
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