ITM2B and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ITM2B	SYNE4
Description		integral membrane protein 2B	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Golgi-associated Vesicle Membrane Integral Component Of Organelle Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Amyloid-beta Binding Protein Binding ATP Binding	Protein Binding
	Biological Process	Nervous System Development Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: APP BCL2 CREB3 KASH5 LMNA NAALADL2 SYNE4	57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648
Entrez ID		9445	163183
HPRD ID		04878	08776
Ensembl ID		ENSG00000136156	ENSG00000181392
Uniprot IDs		A0A384MDP7 Q9Y287	Q8N205
PDB IDs			6R16 6WMD
Enriched GO Terms of Interacting Partners?
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