TP53INP1 and UNC119

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TP53INP1	UNC119
Description		tumor protein p53 inducible nuclear protein 1	unc-119 lipid binding chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Autophagosome Cytosol PML Body Cytoplasmic Vesicle	Spindle Pole Centrosome Cytosol Intercellular Bridge Synapse Spindle Midzone
	Molecular Function	Protein Binding Antioxidant Activity	Protein Binding Lipid Binding
	Biological Process	Autophagosome Assembly Apoptotic Process Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Autophagy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Cellular Response To UV Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Autophagic Cell Death Negative Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Cellular Response To Ethanol Cellular Response To Hydroperoxide Cellular Response To Methyl Methanesulfonate Cellular Oxidant Detoxification Negative Regulation Of Myofibroblast Differentiation	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Alzheimer's disease ( 31473137) Fasting glucose ( 34059833) Hemoglobin levels ( 32327693) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Macular thickness ( 30535121) Platelet distribution width ( 32888494) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 22885922 24509480 30054458 30297969 32499647 20581827 28869590) Urate levels ( 31578528)
Interacting Genes		11 interacting genes: GABARAP GABARAPL1 GABARAPL2 HIPK2 MAP1LC3A MAP1LC3C SEC22A SQSTM1 TP53 UNC119 YPEL3	103 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24
Entrez ID		94241	9094
HPRD ID		09367	04927
Ensembl ID		ENSG00000164938	ENSG00000109103
Uniprot IDs		A0A024R9C8 Q96A56	K7EN86 Q13432
PDB IDs			3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A
Enriched GO Terms of Interacting Partners?
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