TJP2 and SAFB

Number of citations of the paper that reports this interaction (PubMedID 12403786)
43

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		TJP2	SAFB
Description		tight junction protein 2	scaffold attachment factor B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Cell-cell Contact Zone	Nucleus Nucleoplasm Midbody
	Molecular Function	Guanylate Kinase Activity Protein Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Cadherin Binding Cell Adhesion Molecule Binding Protein Tyrosine Kinase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Homotypic Cell-cell Adhesion Maintenance Of Blood-brain Barrier Cell-cell Junction Organization GMP Metabolic Process GDP Metabolic Process Intestinal Absorption Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Cell-cell Adhesion Protein Localization To Cell-cell Junction Positive Regulation Of Blood-brain Barrier Permeability	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Intracellular Estrogen Receptor Signaling Pathway Regulation Of MRNA Processing
Pathways		Signaling by Hippo Apoptotic cleavage of cell adhesion proteins RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Macular thickness ( 30535121) Myopia ( 27182965) Night sleep phenotypes ( 27126917) Refractive error ( 23396134 32231278) Renal sinus fat ( 22044751) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight gain in amisulpride-treated first-episode psychosis ( 32126890)	Mean reticulocyte volume ( 32888494)
Interacting Genes		16 interacting genes: CDK6 CGN CLDN1 CLDN2 CLK1 CTNNA1 EPB41 HGS HSPB1 SAFB SCRIB SH3KBP1 TJP1 YWHAB YWHAG YWHAZ	29 interacting genes: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MIR199A1 MIR363 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7D NCOR1 POLR2A RFX2 SAFB2 SREK1 SRPK1 SRPK2 SRSF9 SUMO2 TAF15 TJP2
Entrez ID		9414	6294
HPRD ID		06369	04205
Ensembl ID		ENSG00000119139	ENSG00000160633
Uniprot IDs		B7Z2R3 B7Z954 Q9UDY2	B7Z2F6 B7ZLP5 Q15424
PDB IDs		2OSG 3E17
Enriched GO Terms of Interacting Partners?
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