PEX16 and PEX19

Number of citations of the paper that reports this interaction (PubMedID 10704444)
81

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		PEX16	PEX19
Description		peroxisomal biogenesis factor 16	peroxisomal biogenesis factor 19
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Brush Border Membrane Protein-containing Complex
	Molecular Function	Protein Binding Protein C-terminus Binding	Protein Binding Peroxisome Membrane Targeting Sequence Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding Protein Carrier Activity
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix Protein To Membrane Docking ER-dependent Peroxisome Organization Protein Import Into Peroxisome Membrane ER-dependent Peroxisome Localization	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Chaperone-mediated Protein Folding Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways		Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import	ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296) SAPHO syndrome ( 33816493)
Interacting Genes		26 interacting genes: AQP6 BDKRB2 CLEC10A CREB3L1 DEXI EBAG9 ERGIC3 FCER1G FFAR2 GPR152 KCNJ6 LEPROTL1 MFSD14B MMGT1 PDZK1IP1 PEX19 PEX3 PGRMC2 REEP4 SLC10A1 SLC10A6 SLC18A1 SLC35C2 TMX2 TNFRSF17 ZDHHC15	39 interacting genes: ABCD1 ABCD2 ABCD3 BCL2L11 CDC25A CDKN2A DLG4 EIF1B F11R FKBP7 GSKIP IFNB1 IL23A IRF3 KIFAP3 MFSD5 NAT8L OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PSORS1C2 PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 SUOX TMEM54 TXN2
Entrez ID		9409	5824
HPRD ID		04526	02610
Ensembl ID		ENSG00000121680	ENSG00000162735
Uniprot IDs		Q9Y5Y5	A0A0S2Z497 P40855
PDB IDs			2W85 2WL8 3AJB 3MK4 5LNF
Enriched GO Terms of Interacting Partners?
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