CIAO1 and SLC4A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CIAO1	SLC4A7
Description		cytosolic iron-sulfur assembly component 1	solute carrier family 4 member 7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm MMXD Complex CIA Complex	Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Stereocilium
	Molecular Function	Protein Binding	Inorganic Anion Exchanger Activity Protein Binding Sodium:bicarbonate Symporter Activity Transmembrane Transporter Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Positive Regulation Of Cell Population Proliferation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer	Inorganic Anion Transport Bicarbonate Transport Sodium Ion Transmembrane Transport Ion Homeostasis Regulation Of Intracellular PH Transmembrane Transport Auditory Receptor Cell Development Anion Transmembrane Transport
Pathways		Cytosolic iron-sulfur cluster assembly	Bicarbonate transporters RHOD GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOJ GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS			Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081) Blood pressure ( 21909110) Breast cancer ( 21263130 29059683 23535729 20453838 19330027) Breast cancer (early onset) ( 24493630) Diastolic blood pressure ( 27841878 21909115 28739976 27618447 27618452 25249183) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hypertension ( 25249183) Lymphocyte counts ( 32888494) Macular telangiectasia type 2 ( 33654266) Macular thickness ( 30535121) Mean arterial pressure ( 29403010 27618448) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (beta blocking agents) ( 31015401) Medication use (diuretics) ( 31015401) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 29403010 30578418) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 28135244 21909115 29403010 28739976 27618452 25249183 30578418) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Urinary potassium excretion ( 31409800) Urinary potassium to creatinine ratio ( 30910378) Uterine fibroids ( 30194396)
Interacting Genes		18 interacting genes: APP CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SF1 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B URI1 WT1	8 interacting genes: CFTR CIAO1 DLG4 KRTAP4-5 MTNR1B SLC4A4 SLC9A3R1 YWHAB
Entrez ID		9391	9497
HPRD ID		16057	04521
Ensembl ID		ENSG00000144021	ENSG00000033867
Uniprot IDs		O76071	B5M450 E9PFN4 Q9Y6M7
PDB IDs		3FM0
Enriched GO Terms of Interacting Partners?
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