ZFYVE9 and ZMYND8

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
HPRD (two hybrid)

		ZFYVE9	ZMYND8
Description		zinc finger FYVE-type containing 9	zinc finger MYND-type containing 8
Image
GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Dendritic Spine Dendritic Shaft
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Methylated Histone Binding Protein N-terminus Binding Lysine-acetylated Histone Binding DNA-binding Transcription Factor Binding
	Biological Process	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport	Negative Regulation Of Cell Migration Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Filopodium Assembly Positive Regulation Of Dendritic Spine Development Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Density Protein 95 Clustering Positive Regulation Of Dendritic Spine Maintenance
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Bipolar disorder ( 34099189) Caffeine consumption from coffee ( 33287642) Daytime nap ( 33568662) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Metabolite levels ( 23823483) Migraine ( 27182965) Parahippocampal gyrus volume ( 31530798) Platelet distribution width ( 32888494) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		40 interacting genes: ANKLE2 ATP6V0B BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NRDC NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	17 interacting genes: ATN1 ATRX CSNK1E ERBB2 FHOD1 FMR1 FXR2 H3C1 MEOX2 PBXIP1 PRKCB RERE SPOP SUMO2 USP7 ZBTB7A ZFYVE9
Entrez ID		9372	23613
HPRD ID		04782	10166
Ensembl ID		ENSG00000157077	ENSG00000101040
Uniprot IDs		O95405	A0A087WVZ6 A6H8Y8 Q2HXV5 Q569J9 Q9ULU4
PDB IDs		1DEV 1MK2 4BKW 5MJY	4COS 5B73 5MQ4 5Y1Z
Enriched GO Terms of Interacting Partners?
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