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ADIPOQ and BCL2L13
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
ADIPOQ
BCL2L13
Description
adiponectin, C1Q and collagen domain containing
BCL2 like 13
Image
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Extracellular Space
Endoplasmic Reticulum
Cell Surface
Collagen-containing Extracellular Matrix
Nucleus
Mitochondrion
Integral Component Of Membrane
Mitochondrial Membrane
Molecular Function
Signaling Receptor Binding
Cytokine Activity
Hormone Activity
Extracellular Matrix Structural Constituent
Protein Binding
Sialic Acid Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Biological Process
Response To Hypoxia
Positive Regulation Of Protein Phosphorylation
Glucose Metabolic Process
Generation Of Precursor Metabolites And Energy
Fatty Acid Beta-oxidation
Signal Transduction
Response To Nutrient
Circadian Rhythm
Response To Bacterium
Response To Sucrose
Response To Glucose
Positive Regulation Of Signal Transduction
Gene Expression
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Kinase A Signaling
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Cholesterol Efflux
Regulation Of Glucose Metabolic Process
Response To Activity
Fatty Acid Oxidation
Negative Regulation Of Cell Migration
Negative Regulation Of Granulocyte Differentiation
Negative Regulation Of Protein Autophosphorylation
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Interleukin-8 Production
Cellular Response To Insulin Stimulus
Positive Regulation Of Myeloid Cell Apoptotic Process
Negative Regulation Of Heterotypic Cell-cell Adhesion
Low-density Lipoprotein Particle Clearance
Response To Tumor Necrosis Factor
Glucose Homeostasis
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of MAP Kinase Activity
Response To Ethanol
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Macrophage Differentiation
Negative Regulation Of Gluconeogenesis
Negative Regulation Of Blood Pressure
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Fatty Acid Metabolic Process
Positive Regulation Of Glucose Import
Negative Regulation Of Hormone Secretion
Negative Regulation Of Inflammatory Response
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Phagocytosis
Negative Regulation Of Synaptic Transmission
Brown Fat Cell Differentiation
Response To Glucocorticoid
Negative Regulation Of ERK1 And ERK2 Cascade
Response To Linoleic Acid
Detection Of Oxidative Stress
Cellular Response To CAMP
Cellular Response To Xenobiotic Stimulus
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Cellular Response To Epinephrine Stimulus
Protein Localization To Plasma Membrane
Negative Regulation Of Intracellular Protein Transport
Positive Regulation Of Lipid Transporter Activity
Positive Regulation Of Cold-induced Thermogenesis
Negative Regulation Of Cold-induced Thermogenesis
Negative Regulation Of Receptor Binding
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Low-density Lipoprotein Receptor Activity
Negative Regulation Of DNA Biosynthetic Process
Positive Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Metanephric Glomerular Visceral Epithelial Cell Development
Positive Regulation Of CAMP-dependent Protein Kinase Activity
Positive Regulation Of Renal Albumin Absorption
Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway
Negative Regulation Of Metanephric Mesenchymal Cell Migration
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Apoptotic Process
Pathways
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Activated partial thromboplastin time (
22703881
)
Adiponectin levels (
21700879
26299439
20876611
20011104
22479202
20018283
19165155
24105470
)
Adiponectin levels (BMI-adjusted) (
26299439
)
Adiponectin levels in pregnancy (
28317342
)
Copper levels (
26025379
)
Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma (
29551627
)
Eosinophil counts (
32888494
)
Granulocyte count (
27863252
)
Hemoglobin levels (
32327693
)
Interleukin-10 levels (
22205395
)
Lymphocyte percentage of white cells (
32888494
)
Monocyte count (
32888494
)
Myeloid white cell count (
27863252
)
Neutrophil count (
32888494
27863252
)
Neutrophil percentage of white cells (
32888494
)
Sum neutrophil eosinophil counts (
27863252
)
White blood cell count (
32888494
)
Interacting Genes
61 interacting genes:
ADIPOR2
AMIGO1
AQP6
ASGR2
BCL2L13
BIK
BNIP3L
BSND
BTNL9
CAMLG
CCDC107
CD200R1
CD79A
CDH13
CLDN9
CLEC10A
CLEC2D
CNR2
COQ9
CPLX4
CREB3L1
CYBC1
ERP29
FAM209A
FASN
FCGR1A
FKBP7
FNDC9
GPR152
GPR42
HSD17B11
IFNGR2
KASH5
KCNK5
KEL
MFF
MFSD14B
MFSD6
MRM1
MS4A3
MUC1
NEMP1
PEX12
PROKR2
PVR
SCN3B
SGTA
SGTB
SIGLEC12
SLC16A2
SLC22A23
SLC35C2
SLC35E3
SYAP1
SYNE4
TMEM179B
TMEM237
TMEM35A
TMPRSS2
TNFSF14
TRIM35
56 interacting genes:
ADIPOQ
AGTRAP
AIG1
APOD
APP
AQP1
BET1
C4orf3
CD53
CLDN19
CRB3
DEFB127
ERG28
ERMP1
FAM210B
FXYD3
FZD7
GABARAPL2
GALNT2
GAST
HMOX2
IL17RA
JAGN1
LAT
LPAR3
MAL
MTNR1B
NINJ2
PLLP
PLN
PLP1
PLPP4
SLC30A8
SLC35A1
SLC35G5
SMIM1
SPOCK1
STX12
STX8
TM6SF2
TMEM128
TMEM14C
TMEM242
TMEM254
TMEM51
TMEM72
TMEM86A
TMEM86B
TMEM97
TMUB2
TNF
TNMD
TRARG1
UPK1B
VAMP3
VAMP4
Entrez ID
9370
23786
HPRD ID
05671
09822
Ensembl ID
ENSG00000181092
ENSG00000099968
Uniprot IDs
A8K660
B2R773
Q15848
A0A087WTL4
A0A087WW80
A0A087WX97
A0A0A0MR90
A8K5Y4
B2RB43
B7Z238
B7Z737
E9PDD6
F6VJB4
Q86T62
Q9BXK5
PDB IDs
4DOU
6U66
6U6N
2IPD
Enriched GO Terms of Interacting Partners
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