MRFAP1 and ABI3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MRFAP1	ABI3
Description		Morf4 family associated protein 1	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Perinuclear Region Of Cytoplasm	Intracellular Anatomical Structure Cytoplasm Postsynaptic Density Membrane Lamellipodium SCAR Complex Dendritic Spine Dendritic Shaft
	Molecular Function	Protein Binding	Protein Binding SH3 Domain Binding Identical Protein Binding Actin Filament Binding
	Biological Process		Defense Response To Tumor Cell Negative Regulation Of Lamellipodium Assembly Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Density Assembly Negative Regulation Of Ruffle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		41 interacting genes: ABI1 ABI2 ABI3 BRK1 C14orf93 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MRFAP1L1 MTIF3 PAM16 PCBD2 PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		93621	51225
HPRD ID		17589	05900
Ensembl ID		ENSG00000179010	ENSG00000108798
Uniprot IDs		A0A087WTY9 B3KQA0 Q9Y605	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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