SYCE1 and NME7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		SYCE1	NME7
Description		synaptonemal complex central element protein 1	NME/NM23 family member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleoplasm Chromosome Cytosol Intracellular Membrane-bounded Organelle	Centrosome Cytosol
	Molecular Function	Protein Binding	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process
Pathways		Meiotic synapsis	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left-handedness ( 32989287) Myocardial infarction ( 33532862) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 33592630 21980494 22672568)
Interacting Genes		49 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 CYTH3 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HOOK1 HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 LMNA MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM1 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	75 interacting genes: AMOTL2 ARHGAP9 BTBD6 CARD10 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC42EP2 CEP72 CFAP141 DDIT4L DDX1 DISC1 DNAI7 EFHC2 FKBP6 FLOT1 FOSL1 FOSL2 GATAD2B GLIS2 GOLGA2 GSC2 HAUS8 IKZF1 IKZF3 INCA1 ISY1-RAB43 KRT18 KRT75 LNX1 MAP4K4 MED11 MED30 MEI4 MEOX2 MYOT NAB2 NEFL NFKBIL1 NIF3L1 NME4 NT5C2 OFD1 PAX4 PIAS2 PICK1 POU6F2 PROSER3 PSMA1 REL RUBCN SHTN1 SNAPIN SNX32 SYCE1 TCF4 TCHP TEKT1 TEPSIN THAP10 TNIP1 TNNI2 TRIM27 TRIM48 TUFT1 YWHAQ ZBTB48 ZNF23 ZNF263 ZNF343 ZNF526 ZNF620
Entrez ID		93426	29922
HPRD ID		12598	11394
Ensembl ID		ENSG00000171772	ENSG00000143156
Uniprot IDs		A0A0B4J1R9 Q8N0S2	A0A024R8Z7 Q9Y5B8
PDB IDs
Enriched GO Terms of Interacting Partners?
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