COPB2 and RGS4

Number of citations of the paper that reports this interaction (PubMedID 10982407)
9

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		COPB2	RGS4
Description		COPI coat complex subunit beta 2	regulator of G protein signaling 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol COPI Vesicle Coat Transport Vesicle	Nucleus Cytoplasm Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Structural Molecule Activity Protein Binding	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Toxin Transport	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Heart Rate Response To Cocaine Response To Morphine Positive Regulation Of GTPase Activity Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transport Negative Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Actin Filament Organization Negative Regulation Of Glycine Import Across Plasma Membrane Negative Regulation Of Potassium Ion Transmembrane Transport Dorsal Root Ganglion Development Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Kawasaki disease ( 22446961) Male-pattern baldness ( 29146897)	Daytime nap ( 33568662) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mTOR inhibitor (rapamycin) ( 24009623)
Interacting Genes		15 interacting genes: ARCN1 COPA COPE MCPH1 MFHAS1 MSRA NDRG1 NFKB1 PRKCE RGS2 RGS4 SACM1L SUMO2 TMED10 WBP2	21 interacting genes: BYSL CALM1 COPB1 COPB2 DDR2 EGFR ERBB3 GABBR1 GNAI1 GNAI2 GNAO1 GNAQ KRIT1 MPZ OSMR PFDN2 PLCB1 PTAFR RRM1 SDHC UAP1
Entrez ID		9276	5999
HPRD ID		06103	03947
Ensembl ID		ENSG00000184432	ENSG00000117152
Uniprot IDs		P35606	A0A024R909 P49798
PDB IDs
Enriched GO Terms of Interacting Partners?
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