CYTH2 and ATP6V0A1

Number of citations of the paper that reports this interaction (PubMedID 21307348)
21

Data Source:
BioGRID (pull down)

		CYTH2	ATP6V0A1
Description		cytohesin 2	ATPase H+ transporting V0 subunit a1
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Growth Cone	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding	Protein Binding Proton Transmembrane Transporter Activity ATPase Binding
	Biological Process	Endocytosis Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity	Vacuolar Acidification Regulation Of Macroautophagy Toxin Transport Proton Transmembrane Transport
Pathways		Intra-Golgi traffic	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Formic acid 1D-myo-inositol 1,4,5-trisphosphate S,S-(2-Hydroxyethyl)Thiocysteine Brefeldin A	Tiludronic acid
Diseases
GWAS		Abstraction and mental flexibility ( 31596458)	Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		33 interacting genes: ADORA2A ALDOA APC ARF1 ARF6 ARFGAP1 ARL4A ARL4D ARRB1 ARRB2 ATP6V0A1 ATP6V0A2 ATP6V0A4 CCDC120 CNKSR1 CUX1 CYTIP DOCK1 GGA3 GNAQ INAVA IPCEF1 ITGB2 MAPK6 NUP62 PIK3CA PNPLA2 PRKCA PRKCB PRKCG PRRG2 TCIRG1 TRIM23	7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267
Entrez ID		9266	535
HPRD ID		03925	01886
Ensembl ID		ENSG00000105443	ENSG00000033627
Uniprot IDs		Q99418	Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs		1PBV 1R8M 1R8Q 1R8S 1S9D 4JMI 4JMO 4JWL 4JXH 4L5M 4Z21	6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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