TIMM50 and PAFAH1B2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TIMM50	PAFAH1B2
Description		translocase of inner mitochondrial membrane 50	platelet activating factor acetylhydrolase 1b catalytic subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Integral Component Of Membrane Nuclear Speck	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Interleukin-2 Receptor Binding Protein Binding Ribonucleoprotein Complex Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Release Of Cytochrome C From Mitochondria Protein Dephosphorylation Mitochondrial Membrane Organization Protein Import Into Mitochondrial Matrix Peptidyl-tyrosine Dephosphorylation	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy
Pathways		Mitochondrial protein import	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		5 interacting genes: DNM1 LY6E-DT PAFAH1B2 RAF1 TNFRSF10B	20 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK KMT2A PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1
Entrez ID		92609	5049
HPRD ID		12118	03940
Ensembl ID		ENSG00000105197	ENSG00000168092
Uniprot IDs		A0A024R0M6 Q3ZCQ8	P68402 V9HW44
PDB IDs			1VYH
Enriched GO Terms of Interacting Partners?
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