SCGB3A1 and MARCO

Number of citations of the paper that reports this interaction (PubMedID 12847263)
21

Data Source:
HPRD (in vivo)

		SCGB3A1	MARCO
Description		secretoglobin family 3A member 1	macrophage receptor with collagenous structure
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome	Collagen Trimer Intracellular Anatomical Structure Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Membrane
	Molecular Function	Cytokine Activity Protein Binding	Amyloid-beta Binding G Protein-coupled Receptor Binding Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Cargo Receptor Activity Pattern Recognition Receptor Activity
	Biological Process	Signal Transduction Negative Regulation Of Cell Growth Regulation Of Cell Population Proliferation Positive Regulation Of Myoblast Fusion	Positive Regulation Of Protein Phosphorylation Endocytosis Receptor-mediated Endocytosis Phagocytosis, Engulfment Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Apoptotic Cell Clearance Innate Immune Response Positive Regulation Of ERK1 And ERK2 Cascade Amyloid-beta Clearance
Pathways			Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs			Titanium dioxide Silicon dioxide
Diseases
GWAS		Blood protein levels ( 30072576) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Lung function (FVC) ( 30061609) Medication use (adrenergics, inhalants) ( 31015401) Triglyceride levels ( 32203549)
Interacting Genes		10 interacting genes: AURKA BAG4 FBXW7 FGFR4 MARCO NOTCH3 RHBDD2 TGFB1 TSG101 XRCC3	4 interacting genes: NAT14 SAP130 SCGB3A1 SCGB3A2
Entrez ID		92304	8685
HPRD ID		05932	05337
Ensembl ID		ENSG00000161055	ENSG00000019169
Uniprot IDs		Q96QR1	Q4ZG40 Q9UEW3
PDB IDs
Enriched GO Terms of Interacting Partners?
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