MAGI1 and CLCN5

Number of citations of the paper that reports this interaction (PubMedID 9169421)
44

Data Source:
HPRD (in vitro)

		MAGI1	CLCN5
Description		membrane associated guanylate kinase, WW and PDZ domain containing 1	chloride voltage-gated channel 5
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Cell Junction Cell Projection Cell Periphery	Golgi Membrane Lysosomal Membrane Early Endosome Golgi Apparatus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Endosome Membrane Membrane Apical Part Of Cell
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Alpha-actinin Binding Molecular Adaptor Activity	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Antiporter Activity Solute:proton Antiporter Activity Identical Protein Binding
	Biological Process	Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Protein-containing Complex Assembly	Chloride Transport Endocytosis Excretion Ion Transmembrane Transport Proton Transmembrane Transport
Pathways			Stimuli-sensing channels
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 28334814) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cirrhosis (alcohol related) ( 32853455) Cobalt levels ( 26025379) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Cortical surface area (MOSTest) ( 32665545) Crohn's disease-related phenotypes ( 25557950) Declining hemoglobin trajectory in blood donors ( 33491795) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Knee osteoarthritis ( 28916551) Neurociticism ( 29500382) Neuroticism ( 25993607) Nicotine dependence symptom count ( 25555482) Ocular sarcoidosis ( 32141793) Ocular sarcoidosis in sarcoidosis ( 32141793) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 23534349) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tinnitus ( 33742053)	Height ( 28552196) Hip circumference adjusted for BMI ( 28552196) Red blood cell count ( 32888494)
Interacting Genes		27 interacting genes: ACTN4 ADGRB1 AMOT ASIC3 ATF6 ATN1 CLCN5 CRHR1 CTNNB1 DAG1 GBP2 IGSF5 IL6R LRP2 NET1 PRRG4 RAC1 RASA1 RASL11B RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2	5 interacting genes: CFL1 CXCR4 MAGI1 WWP1 WWP2
Entrez ID		9223	1184
HPRD ID		04020	02053
Ensembl ID		ENSG00000151276	ENSG00000171365
Uniprot IDs		Q96QZ7	A8K4H5 B3KRR2 P51795 V9GYG7
PDB IDs		1WBP 2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU 5N7D 5N7F 5N7G 6TWU 6TWX 6TWY	2J9L 2JA3
Enriched GO Terms of Interacting Partners?
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