SCAF11 and TUBA1C

		SCAF11	TUBA1C
Description		SR-related CTD associated factor 11	tubulin alpha 1c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Body	Nucleus Cytoplasm Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Vesicle
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cell Division
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs			Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS		Coronary artery disease ( 29212778) Fish- and plant-related diet ( 32066663) Hemoglobin levels ( 32327693) Morning person ( 30696823) Multiple sclerosis ( 31604244) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278)	Brain morphology (MOSTest) ( 32665545) Cancer (pleiotropy) ( 27197191) Mean corpuscular hemoglobin ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252)
Interacting Genes		13 interacting genes: ATXN1L PSEN1 SHMT2 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 SUMO2 TUBA1C U2AF2	16 interacting genes: ACVR1B AMHR2 AQP5 CDKN2A CRK ESR1 KMT2D OGT PRKAG1 SCAF11 SHANK3 SHMT2 SUMO2 SUMO4 TUBA1A VIM
Entrez ID		9169	84790
HPRD ID		04720	06747
Ensembl ID		ENSG00000139218	ENSG00000167553
Uniprot IDs		Q99590	B7Z1K5 F5H5D3 Q9BQE3
PDB IDs
Enriched GO Terms of Interacting Partners?
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