ATPAF2 and CDK2AP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATPAF2	CDK2AP1
Description		ATP synthase mitochondrial F1 complex assembly factor 2	cyclin dependent kinase 2 associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding DNA Polymerase Binding
	Biological Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly	Positive Regulation Of Protein Phosphorylation DNA-dependent DNA Replication Cell Cycle
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Schizophrenia ( 25056061 29483656 23974872) Total cholesterol levels ( 29615537) Tourette syndrome ( 30818990)
Interacting Genes		74 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TERT TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655	13 interacting genes: ATPAF2 CARD9 CCDC136 CDK2 CDK2AP2 GRM3 MRFAP1L1 NTAQ1 PICK1 POLA1 SPG21 USP20 ZNF420
Entrez ID		91647	8099
HPRD ID		10599	03726
Ensembl ID		ENSG00000171953	ENSG00000111328
Uniprot IDs		Q8N5M1	O14519
PDB IDs			2KW6
Enriched GO Terms of Interacting Partners?
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