DYRK1B and DCAF7

Number of citations of the paper that reports this interaction (PubMedID 14593110)
41

Data Source:
HPRD (in vitro)

		DYRK1B	DCAF7
Description		dual specificity tyrosine phosphorylation regulated kinase 1B	DDB1 and CUL4 associated factor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Protein Phosphorylation Myoblast Fusion Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Adipose Tissue Development	Protein Ubiquitination
Pathways			Association of TriC/CCT with target proteins during biosynthesis Neddylation
Drugs		Fostamatinib
Diseases
GWAS		Macular thickness ( 30535121)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		12 interacting genes: DCAF7 GSC2 HDAC5 ID2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP	17 interacting genes: ACE AIFM1 APP ATP13A2 ATP5PD BMPR1B CBX1 DYRK1B LIG1 PCTP PWP2 SPDYA TANC2 TK1 TLK2 YWHAB YWHAG
Entrez ID		9149	10238
HPRD ID		05188	09340
Ensembl ID		ENSG00000105204	ENSG00000136485
Uniprot IDs		A0A024R0I0 A0A024R0J6 A0A024R0M8 Q9Y463	P61962
PDB IDs
Enriched GO Terms of Interacting Partners?
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