SYNGR2 and CCR4

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		SYNGR2	CCR4
Description		synaptogyrin 2	C-C motif chemokine receptor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Integral Component Of Membrane Synaptic Vesicle Membrane Neuromuscular Junction Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Neuronal Cell Body
	Molecular Function	Protein Binding	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Regulated Exocytosis Synaptic Vesicle Membrane Organization	Neuron Migration Tolerance Induction Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Radiation Response To Bacterium Calcium-mediated Signaling Response To Antibiotic Homeostasis Of Number Of Cells Positive Regulation Of Positive Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Mogamulizumab FLX475
Diseases
GWAS		Adenocarcinoma ( 26732429) Lung cancer ( 26732429) Red blood cell count ( 32888494)	Asthma ( 31959851) Celiac disease ( 22057235 20190752) Multiple sclerosis ( 24076602) Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (perceptual aberration scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (revised physical anhedonia scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (revised social anhedonia scale) ( 28525603)
Interacting Genes		9 interacting genes: BDKRB2 C5AR2 CCR4 DRD2 F2RL1 FATE1 GPR35 LTB4R2 SCARA3	37 interacting genes: ATP2A2 B3GAT3 BSG CACNA1H CCKBR CCL17 CCL22 CCL3 CCL5 CDK10 CH25H CLASP2 CLPTM1 CNTNAP1 DHCR24 ERGIC3 FAM234A FXR2 GHITM GRK2 GRK3 NAT14 NDRG2 NSUN2 PKM PRDX1 PTOV1 RTN1 RTN4 SLC12A5 SLC3A2 SLCO4A1 STIMATE SYNGR2 TMEM101 TMEM11 TRARG1
Entrez ID		9144	1233
HPRD ID		04891	05324
Ensembl ID		ENSG00000108639	ENSG00000183813
Uniprot IDs		A0A024R8T9 O43760	A0N0Q1 P51679
PDB IDs
Enriched GO Terms of Interacting Partners?
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