ATG12 and ATG10

Number of citations of the paper that reports this interaction (PubMedID 12482611)
18

Data Source:
HPRD (in vivo, in vitro)

		ATG12	ATG10
Description		autophagy related 12	autophagy related 10
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex	Cytosol
	Molecular Function	Protein Binding	Protein Binding Atg12 Transferase Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Autophagy Of Nucleus	Protein Lipidation Autophagy ER Overload Response Protein Transport Macroautophagy Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation
Pathways		Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling	Macroautophagy Macroautophagy
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)	Adventurousness ( 30643258) Airway imaging phenotypes ( 26030696) Breast cancer ( 25751625 29059683) Carotid intima media thickness (mean) ( 31801372) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels in HIV infection ( 33109212) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		16 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2 SRP19	5 interacting genes: ATG12 ATG5 ATG7 DNAI1 IRGM
Entrez ID		9140	83734
HPRD ID		08496	16497
Ensembl ID		ENSG00000145782	ENSG00000152348
Uniprot IDs		O94817	Q9H0Y0
PDB IDs		4GDK 4GDL 4NAW
Enriched GO Terms of Interacting Partners?
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