KRT75 and ZWINT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRT75	ZWINT
Description		keratin 75	ZW10 interacting kinetochore protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Kinetochore Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Protein N-terminus Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Signaling Mitotic Spindle Assembly Checkpoint Signaling Cell Division Establishment Of Localization In Cell
Pathways		Keratinization Formation of the cornified envelope	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Cardiac hypertrophy ( 21348951) Cognitive function in longevity ( 33607172) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Liver fibrosis (total hepatic collagen content) ( 32953199)
Interacting Genes		124 interacting genes: - ABI2 AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf109 C1orf216 C2CD6 CAMK2A CARD10 CARD9 CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DES DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT3 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C PRPH RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 USHBP1 VIM WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT	17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10
Entrez ID		9119	11130
HPRD ID		11057	18366
Ensembl ID		ENSG00000170454	ENSG00000122952
Uniprot IDs		O95678	O95229
PDB IDs
Enriched GO Terms of Interacting Partners?
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