IGFN1 and HOXD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IGFN1	HOXD3
Description		immunoglobulin like and fibronectin type III domain containing 1	homeobox D3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Z Disc Synapse	Chromatin Nucleus Nucleoplasm Aggresome Nuclear Body
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Biological_process Retina Layer Formation	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Cell-matrix Adhesion Notch Signaling Pathway Anterior/posterior Pattern Specification Positive Regulation Of Gene Expression Thyroid Gland Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cartilage Development
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Asthma ( 29273806) Height ( 28552196)	Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 29146897 28196072) Mucinous ovarian carcinoma ( 26075790) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Ovarian cancer ( 20852632) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		40 interacting genes: BANP BLZF1 C19orf54 COG6 CRX DDAH2 FXR2 GOLGA2 HIVEP1 HOXA1 HOXD3 KCTD9 KIFC3 KRT39 KRTAP6-2 LHX9 LZTS2 MEOX2 MID2 MYOD1 NHLRC4 PIBF1 PNMA1 POF1B POU6F2 PRKAR1B PRR23B SERTAD2 SPAG5 TAX1BP1 TRIM21 TRIM27 TRIM35 TRIM42 TRIP13 TSC1 UBAP2 USP54 ZNF620 ZNF688	7 interacting genes: ALX4 DDB1 HMGB1 HOXC8 IGFN1 NFKBID SMARCD1
Entrez ID		91156	3232
HPRD ID		16812	00863
Ensembl ID		ENSG00000163395	ENSG00000128652
Uniprot IDs		Q86VF2	P31249
PDB IDs
Enriched GO Terms of Interacting Partners?
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