LDB2 and SSBP4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		LDB2	SSBP4
Description		LIM domain binding 2	single stranded DNA binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Plasma Membrane Cell Leading Edge	Nucleus
	Molecular Function	Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding	Single-stranded DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Hair Follicle Development Nervous System Development Epithelial Structure Maintenance Regulation Of Cell Migration Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292) Liver fibrosis (total hepatic collagen content) ( 32953199) Number of sexual partners ( 30643258) QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference ( 28552196)	Alzheimer's disease (late onset) ( 30820047) Basophil count ( 32888494) Breast cancer ( 23535729) Intake of total sugars ( 31005972) Monocyte count ( 27863252) Systemic lupus erythematosus ( 33272962 33536424 28714469)
Interacting Genes		29 interacting genes: C14orf119 CETN3 DGCR6L EGLN3 EPM2AIP1 EXOC3L1 GGACT HDAC7 ISL1 LHX4 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LNX1 NTAQ1 PSMB1 RASIP1 RILP RLIM SDCBP SMARCD1 SSBP2 SSBP3 SSBP4 TSNAX TTC19	8 interacting genes: IL36RN LDB1 LDB2 MYO15B PIK3R3 PIN1 SPG21 TFAP2B
Entrez ID		9079	170463
HPRD ID		16022	09579
Ensembl ID		ENSG00000169744	ENSG00000130511
Uniprot IDs		B7Z6D0 E9PFI4 G5E9Y7 O43679	Q9BWG4
PDB IDs
Enriched GO Terms of Interacting Partners?
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