ZNF835 and CLK3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF835	CLK3
Description		zinc finger protein 835	CDC like kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Acrosomal Vesicle Nucleus Nucleoplasm Membrane Nuclear Speck Intermediate Filament Cytoskeleton
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation
Pathways
Drugs			K-00546 ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate Fostamatinib
Diseases
GWAS		Vaginal microbiome composition (G. vaginalis) ( 32723796) Western dietary pattern ( 28644415)	Bladder cancer ( 25281661) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Celiac disease ( 22057235) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712)
Interacting Genes		67 interacting genes: BEGAIN BYSL CABP5 CCDC136 CCDC57 CCDC6 CCNDBP1 CDR2L CEP70 CIB3 CLK3 CYSRT1 DEUP1 FSD2 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GUCD1 HAP1 HOOK2 HOXB1 HSF2BP IKBKG IL16 KIFC3 KRT31 KRTAP12-3 KRTAP4-5 LDOC1 MAGOHB MKRN3 MYF5 OSBPL3 POLR1C PRDM14 RINT1 RNF187 RUNDC3A SHCBP1L SHFL SPATA2 STAMBPL1 STX1A TEX12 TLE5 TRAF4 TRIM23 TRIM41 TSPYL2 TULP3 TXK U2AF2 YJU2B ZNF121 ZNF202 ZNF343 ZNF497 ZNF524 ZNF526 ZNF552 ZNF572 ZNF629 ZNF71 ZNF768 ZNF792 ZNF837	41 interacting genes: APP CHERP CLASRP CLK2 DDIT4L HOXB6 HOXB7 HOXC4 INCA1 KRTAP10-3 LNX1 NEDD4 NKAPL NXF1 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RNF8 RNPS1 RSRP1 SAG SDCBP SH2B2 SLAMF7 SNIP1 SNRNP35 SRPK2 SRSF10 SRSF3 SRSF8 SUV39H1 TINF2 TRA2B USP13 YWHAG ZNF263 ZNF473 ZNF777 ZNF835
Entrez ID		90485	1198
HPRD ID		12521	04290
Ensembl ID		ENSG00000127903	ENSG00000179335
Uniprot IDs		Q9Y2P0	B3KRI8 P49761
PDB IDs			2EU9 2EXE 2WU6 2WU7 3RAW 6FT7 6FYP 6FYR 6KHF 6RCT 6YTW 6YTY 6YU1 6Z2V 6Z51 6Z52 6Z53 6Z54 6Z55
Enriched GO Terms of Interacting Partners?
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