SH2D2A and PPP1R21

Number of citations of the paper that reports this interaction (PubMedID 25814554)
26

Data Source:
BioGRID (two hybrid)

		SH2D2A	PPP1R21
Description		SH2 domain containing 2A	protein phosphatase 1 regulatory subunit 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Early Endosome Membrane
	Molecular Function	Protein Binding SH3 Domain Binding
	Biological Process	Angiogenesis Signal Transduction Cell Population Proliferation Cell Differentiation
Pathways		VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) SjÃ¶gren's syndrome ( 28076899)	Chronotype ( 30696823) Colorectal cancer ( 30529582) Educational attainment ( 27046643) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Joint mobility (Beighton score) ( 27182965) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin concentration ( 29403010) Prudent dietary pattern ( 28644415) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		35 interacting genes: APPL1 AR ARID5A CRK DAPK1 EGFR ERBB2 ERBB3 ERBB4 GAB1 ITK KDR KIT LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MET MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1 ZYG11B	6 interacting genes: FBXO7 MTNR1B RTN4 SH2D2A SH3GL2 ZDHHC17
Entrez ID		9047	129285
HPRD ID		05152	17294
Ensembl ID		ENSG00000027869	ENSG00000162869
Uniprot IDs		Q5UBZ2 Q5UBZ3 Q9NP31	Q6ZMI0
PDB IDs
Enriched GO Terms of Interacting Partners?
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