TAF1A and SET

Number of citations of the paper that reports this interaction (PubMedID 11163245)
177

Data Source:
BioGRID (biochemical, pull down)
HPRD (in vitro, in vivo)

		TAF1A	SET
Description		TATA-box binding protein associated factor, RNA polymerase I subunit A	SET nuclear proto-oncogene
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Nucleoplasm Microtubule Cytoskeleton	Chromatin Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding	DNA Binding Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding
	Biological Process	Transcription By RNA Polymerase I Transcription By RNA Polymerase II	DNA Replication Nucleosome Assembly Nucleosome Disassembly Negative Regulation Of Histone Acetylation Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Trunk fat mass ( 28552196)	Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)
Interacting Genes		20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4-16 H4C1 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF	69 interacting genes: ANP32A APEX1 APP CALM1 CDCA8 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 ENO1 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H1-1 H2BC1 H3-3A H3-4 H4-16 H4C14 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PAX6 PIK3CG PPP2CA PPP2R1B PRKAR1A PTEN PTMA RAC1 REPIN1 SDCBP SETBP1 SGO1 SGO2 TAF1A TERF1 TERF2 TERF2IP TEX35 THAP7 TLE5 TREX1 TRIM55 TRIM63 UBE3A UCHL5 XRCC6 ZNF17 ZNF438 ZNF85
Entrez ID		9015	6418
HPRD ID		05362	09023
Ensembl ID		ENSG00000143498	ENSG00000119335
Uniprot IDs		A8K4K5 B4DS21 Q15573	A0A024R895 A0A0C4DFV9 Q01105 Q5VXV3
PDB IDs			2E50
Enriched GO Terms of Interacting Partners?
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