MGAM and GPR42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MGAM	GPR42
Description		maltase-glucoamylase	G protein-coupled receptor 42
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Integral Component Of Plasma Membrane
	Molecular Function	Catalytic Activity Glucan 1,4-alpha-glucosidase Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Alpha-1,4-glucosidase Activity Protein Binding Carbohydrate Binding Maltose Alpha-glucosidase Activity	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Maltose Metabolic Process Starch Catabolic Process	G Protein-coupled Receptor Signaling Pathway
Pathways		Digestion of dietary carbohydrate Neutrophil degranulation
Drugs		Acarbose Miglitol Voglibose
Diseases
GWAS		1,5-anhydroglucitol levels ( 28588231) Anorexia nervosa ( 23568457) Blood metabolite levels ( 24816252) Idiopathic dilated cardiomyopathy ( 29495422)
Interacting Genes		8 interacting genes: AQP6 ARF6 CPLX4 CREB3L1 GPR42 NCF1 SLC18A1 TMEM14B	104 interacting genes: ADIPOQ ALOX5AP ANKRD46 APOD ATP13A1 ATP4B ATP6V0B ATP6V0C BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD300C CD79A CLCA4 CLEC2D COMT CTXN3 CXCL16 CXCL9 DRAM1 EFNA5 EMP1 ERMP1 FAM3C FXYD3 FXYD6 GJB2 GOSR2 GPR37L1 GYPC IER3IP1 IGFBP5 IL1RL1 ITGAM JPH1 KCNA1 KLRG1 LAT LEPROTL1 LHFPL5 LNPEP LTC4S MFSD5 MFSD6 MGAM MS4A1 NDUFB11 NINJ2 NRM NSG1 PAEP PLP1 PLPP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SCD SERINC1 SERP2 SERTM1 SLC30A2 SLC30A3 SLC30A8 SLC35E4 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC41A2 SMCO4 SMIM3 STATH STRIT1 STX8 SYNDIG1 SYNGR1 TEX264 TF TM4SF4 TMBIM6 TMEM140 TMEM147 TMEM182 TMEM19 TMEM237 TMEM239 TMEM242 TMEM262 TMEM30B TMEM60 TMEM65 TRARG1 TREX1 TSPO2 YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZFPL1
Entrez ID		8972	2866
HPRD ID		01104	16033
Ensembl ID		ENSG00000257335	ENSG00000126251
Uniprot IDs		E7ER45 O43451	A0A0K0PUY3 O15529
PDB IDs		2QLY 2QMJ 3CTT 3L4T 3L4U 3L4V 3L4W 3L4X 3L4Y 3L4Z 3TON 3TOP
Enriched GO Terms of Interacting Partners?
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