TOP3B and FASTK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TOP3B	FASTK
Description		DNA topoisomerase III beta	Fas activated serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Nucleus	Mitochondrial Matrix Ribonucleoprotein Granule
	Molecular Function	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Protein Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Fas-activated Serine/threonine Kinase Activity
	Biological Process	DNA Topological Change Chromosome Segregation	Mitochondrial RNA Processing Protein Phosphorylation Regulation Of RNA Splicing Regulation Of Mitochondrial MRNA Stability Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813) Bipolar disorder ( 31043756) Diastolic blood pressure ( 29208002) Response to selective serotonin reuptake inhibitors in depression ( 27622933)	Eyebrow thickness ( 26926045)
Interacting Genes		24 interacting genes: ADAMTSL4 AXIN2 BHLHB9 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF250 ZNF408	9 interacting genes: CALCOCO2 CHERP ESRRG MDFI PRPF31 RBPMS TIA1 TOP3B WIPF1
Entrez ID		8940	10922
HPRD ID		04662	07368
Ensembl ID		ENSG00000100038	ENSG00000164896
Uniprot IDs		A0A024R1C2 A8K4N2 O95985	A0A090N8I0 A0A090N8Z7 Q14296
PDB IDs		5GVC 5GVE
Enriched GO Terms of Interacting Partners?
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