APLN and GET3

Number of citations of the paper that reports this interaction (PubMedID 22505607)
30

Data Source:
BioGRID (pull down)

		APLN	GET3
Description		apelin	guided entry of tail-anchored proteins factor 3, ATPase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm	Nucleoplasm Nucleolus Cytoplasm GET Complex Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Hormone Activity Apelin Receptor Binding Identical Protein Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	Angiogenesis Regulation Of The Force Of Heart Contraction Negative Regulation Of Systemic Arterial Blood Pressure Immune Response Signal Transduction Gastrulation Lactation Positive Regulation Of Heart Rate Negative Regulation Of Gene Expression Positive Regulation Of Heat Generation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphorylation Drinking Behavior Negative Regulation Of Blood Pressure Positive Regulation Of Heart Contraction Negative Regulation Of Vasoconstriction Positive Regulation Of Corticotropin Secretion Positive Regulation Of Corticotropin-releasing Hormone Secretion Apelin Receptor Signaling Pathway Coronary Vasculature Development Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Endothelial Cell Proliferation	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			ATP
Diseases
GWAS
Interacting Genes		8 interacting genes: APLNR GET3 MDFI PLSCR4 PSMA3 RBPMS TRIM55 TRIM63	41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3
Entrez ID		8862	439
HPRD ID		02246	03555
Ensembl ID		ENSG00000171388	ENSG00000198356
Uniprot IDs		Q9ULZ1	O43681
PDB IDs			6SO5
Enriched GO Terms of Interacting Partners?
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