TRIM24 and TRIM33

Number of citations of the paper that reports this interaction (PubMedID 12096914)
38

Data Source:
HPRD (in vitro, in vivo)

		TRIM24	TRIM33
Description		tripartite motif containing 24	tripartite motif containing 33
Image
GO Annotations	Cellular Component	Euchromatin Nucleus Nucleoplasm Perichromatin Fibrils Cytosol	Nucleus Nucleoplasm
	Molecular Function	P53 Binding Chromatin Binding Transcription Coactivator Activity Protein Kinase Activity Signaling Receptor Binding Protein Binding Zinc Ion Binding Nuclear Receptor Binding Estrogen Response Element Binding Methylated Histone Binding Ubiquitin Protein Ligase Activity Lysine-acetylated Histone Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Co-SMAD Binding R-SMAD Binding
	Biological Process	Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Protein Ubiquitination Protein Catabolic Process Regulation Of Protein Stability Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Calcium Ion Homeostasis Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Regulation Of Signal Transduction By P53 Class Mediator	Negative Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Transcription, DNA-templated
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by BRAF and RAF1 fusions	Downregulation of SMAD2/3:SMAD4 transcriptional activity
Drugs
Diseases
GWAS		Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Quantitative traits ( 19197348)	Autism ( 24189344) Carotid intima media thickness x smoking interaction ( 32117412) Chronotype ( 30696823) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		55 interacting genes: AR ATF4 BRCA1 BRD7 CBX1 CBX3 CBX5 CREBBP ESR1 ESR2 FBN2 FOSL1 GTF2E1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HNF4A HSPA1A HSPB1 IFT88 MRPS33 MTNR1B NFE2L2 NR2F2 NR3C1 NR3C2 PGR PML PPARG RARA RNF141 RNF181 RXRA STAT6 SUMO1 TAF11 TAF1B TAF1C TAF7 THRA TRAF3 TRIM28 TRIM33 TRIM8 UBE2D1 UBE2I UBE2U VDR ZNF10	13 interacting genes: CHD1L CTNNB1 ERG H3C1 NLGN3 RASGRP1 SMAD3 TRIM24 UBE2D2 UBE2D3 UBE2E1 UBE2N VTCN1
Entrez ID		8805	51592
HPRD ID		04556	10423
Ensembl ID		ENSG00000122779	ENSG00000197323
Uniprot IDs		A0A024R784 O15164	B3KN30 Q9UPN9
PDB IDs		2YYN 3O33 3O34 3O35 3O36 3O37 4YAB 4YAD 4YAT 4YAX 4YBM 4YBS 4YBT 4YC9 4ZQL 5H1T 5H1U 5H1V	3U5M 3U5N 3U5O 3U5P 5MR8
Enriched GO Terms of Interacting Partners?
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