RTCA and MIR17

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		RTCA	MIR17
Description		RNA 3'-terminal phosphate cyclase	microRNA 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Mitochondrion Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding RNA-3'-phosphate Cyclase Activity ATP Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	RNA Processing	Negative Regulation Of Systemic Arterial Blood Pressure Outflow Tract Morphogenesis Negative Regulation Of Gene Expression Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of Transporter Activity Negative Regulation Of Toll-like Receptor Signaling Pathway Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Blood Pressure Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Phagocytosis Cellular Response To Lipopolysaccharide Cellular Response To Hypoxia Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Positive Regulation Of Metalloendopeptidase Activity Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Apoptosome Assembly Positive Regulation Of Pulmonary Blood Vessel Remodeling Positive Regulation Of Smooth Muscle Hypertrophy Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport Negative Regulation Of Cellular Senescence Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Interacting Genes		48 interacting genes: MIR1-1 MIR106B MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR199A1 MIR199A2 MIR19B2 MIR200A MIR205 MIR20B MIR21 MIR214 MIR222 MIR25 MIR29B2 MIR29C MIR31 MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR92A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OTX2	84 interacting genes: AIMP1 APOBEC3B ATXN2L C1QBP CELF1 CPSF6 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRMT1L UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		8634	406952
HPRD ID		15280
Ensembl ID		ENSG00000137996	ENSG00000284536
Uniprot IDs		O00442
PDB IDs
Enriched GO Terms of Interacting Partners?
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