ASMTL and HLA-DRB4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ASMTL	HLA-DRB4
Description		acetylserotonin O-methyltransferase like	major histocompatibility complex, class II, DR beta 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Lysosomal Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Molecular_function Protein Binding O-methyltransferase Activity NADH Pyrophosphatase Activity DTTP Diphosphatase Activity UTP Diphosphatase Activity Nucleoside-triphosphate Diphosphatase Activity	MHC Class II Protein Complex Binding
	Biological Process	Biological_process Nucleotide Metabolic Process Methylation	Adaptive Immune Response Immunoglobulin Production Involved In Immunoglobulin-mediated Immune Response Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Activation
Pathways			Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling
Drugs			1D09C3 Coccidioides immitis spherule
Diseases
GWAS
Interacting Genes		10 interacting genes: APP GORASP2 HLA-DRB4 KRT31 KRT34 KRT40 PNMA1 REL TDO2 ZNF655	3 interacting genes: ASMTL CTAG1B MAGEA6
Entrez ID		8623	3126
HPRD ID		02156	09986
Ensembl ID		ENSG00000169093
Uniprot IDs		B3KM43 O95671	P13762 X5D2U9
PDB IDs		2P5X
Enriched GO Terms of Interacting Partners?
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