CDK13 and CHMP4A

Number of citations of the paper that reports this interaction (PubMedID 16730941)
66

Data Source:
HPRD (two hybrid)

		CDK13	CHMP4A
Description		cyclin dependent kinase 13	charged multivesicular body protein 4A
Image
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Cyclin K-CDK13 Complex Extracellular Region Extracellular Space Nucleus Nucleoplasm Golgi Apparatus Cytosol Cyclin/CDK Positive Transcription Elongation Factor Complex Nuclear Speck Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Ficolin-1-rich Granule Lumen	ESCRT III Complex Nucleus Cytoplasm Endosome Multivesicular Body Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane
	Molecular Function	RNA Binding Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Protein Kinase Binding Cyclin Binding Protein Serine Kinase Activity	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Transcription Elongation From RNA Polymerase II Promoter Protein Phosphorylation Regulation Of Mitotic Nuclear Division Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Hemopoiesis Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Phosphorylation Of RNA Polymerase II C-terminal Domain Negative Regulation Of Stem Cell Differentiation	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Macroautophagy Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Protein Polymerization Midbody Abscission Plasma Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagosome Assembly
Pathways		TP53 Regulates Transcription of DNA Repair Genes Neutrophil degranulation	Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Plateletcrit ( 32888494) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		4 interacting genes: CHMP4A PRPF40A SRPK2 TRIM7	15 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 GCH1 NTAQ1 NUTF2 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		8621	29082
HPRD ID		04496	16597
Ensembl ID		ENSG00000065883	ENSG00000254505
Uniprot IDs		A0A024RA66 A0A024RA85 Q14004 Q9BVE2	Q9BY43
PDB IDs		5EFQ	3C3O 5MK1
Enriched GO Terms of Interacting Partners?
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