TCAP and CDCA4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TCAP	CDCA4
Description		titin-cap	cell division cycle associated 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Z Disc I Band	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein-macromolecule Adaptor Activity Titin Binding BMP Binding Transmembrane Transporter Binding FATZ Binding Titin Z Domain Binding	Protein Binding Transcription Regulator Activity
	Biological Process	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Cell Development Cardiac Muscle Contraction Protein-containing Complex Assembly	Chromatin-mediated Maintenance Of Transcription
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Ulcerative colitis ( 20228799)	Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Leukocyte telomere length ( 32109421)
Interacting Genes		39 interacting genes: ADPGK ANKRD2 ASB6 ATXN1 BLZF1 C19orf54 CDCA4 CHORDC1 CRK ENO1 ENO3 FAM153B FAS FYN GSK3B HSPA8 HSPB2 HSPB3 HSPG2 IKZF3 KLHL41 KRTAP19-7 LAMTOR5 LHX4 MDM2 MSTN MYOZ1 MYOZ3 NUP133 PAX7 PDPK1 RELA SAPCD1 SIVA1 TRIM54 TRIM55 TRIM63 TTC19 TTN	25 interacting genes: BFSP2 C1orf109 DOK5 ENKD1 FAM222B FARS2 FNDC11 KAT2B KDM1A KLHL42 MKRN3 PARD6B PRMT6 SEPHS1 SHC3 SUOX SUPT7L SUV39H1 SUV39H2 TCAP TRIM28 TXN2 XPO1 YPEL3 ZNF451
Entrez ID		8557	55038
HPRD ID		05133	13015
Ensembl ID		ENSG00000173991	ENSG00000170779
Uniprot IDs		A2TDC0 O15273	A0A024R6P3 Q9BXL8
PDB IDs		1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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