EAF1 and SRP14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EAF1	SRP14
Description		ELL associated factor 1	signal recognition particle 14
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Extracellular Region Nucleus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Transcription Elongation Regulator Activity Protein Binding	RNA Binding Protein Binding 7S RNA Binding Endoplasmic Reticulum Signal Peptide Binding
	Biological Process	Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Protein Targeting To ER
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Neutrophil degranulation
Drugs			Artenimol
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Ewing sarcoma ( 22327514) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alanine transaminase) ( 33972514) Obesity-related traits ( 23251661) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620	8 interacting genes: CALM1 EAF1 IL7R NSFL1C PTEN SPANXN2 SRP9 TLE3
Entrez ID		85403	6727
HPRD ID		12209	02831
Ensembl ID		ENSG00000144597	ENSG00000140319
Uniprot IDs		Q96JC9	P37108
PDB IDs			1E8O 1E8S 1RY1 4UYJ 4UYK 5AOX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?