CBX4 and MX1

Number of citations of the paper that reports this interaction (PubMedID 25447205)
6

Data Source:
BioGRID (two hybrid)

		CBX4	MX1
Description		chromobox 4	MX dynamin like GTPase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Nuclear Speck PcG Protein Complex PRC1 Complex	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Microtubule Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding Chromatin Binding Transcription Corepressor Activity Single-stranded RNA Binding Protein Binding SUMO Transferase Activity Enzyme Binding SUMO Binding Methylated Histone Binding Phosphoprotein Binding SUMO Ligase Activity	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Protein Sumoylation Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated	Apoptotic Process Defense Response Signal Transduction Response To Virus Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response
Pathways		Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
Interacting Genes		25 interacting genes: ARID3C CBS CHD3 CREBBP CSNK2B CTBP1 CTBP2 FHL1 H3-4 KMT2A LNX2 MBD1 MED9 MX1 RB1 RING1 RNF2 SATB1 SKIL SPOP SUV39H1 TRIM21 UBE2I ZBED1 ZEB2	55 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CCL16 CD5 CHD3 DAXX DCP2 EPM2AIP1 FANCA FXR1 GGPS1 GMEB1 GPC4 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PIAS1 PIAS2 PLRG1 PRDX6 PSD3 PSG9 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZFP36 ZNF251 ZNF623
Entrez ID		8535	4599
HPRD ID		04357	00919
Ensembl ID		ENSG00000141582	ENSG00000157601
Uniprot IDs		A0A0S2Z5B2 O00257	P20591
PDB IDs		2K28 3I8Z 5EPL	3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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