SMIM3 and LPAR6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMIM3	LPAR6
Description		small integral membrane protein 3	lysophosphatidic acid receptor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding	G Protein-coupled Receptor Activity Protein Binding Lysophosphatidic Acid Receptor Activity
	Biological Process		Blastocyst Hatching Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways			G alpha (q) signalling events P2Y receptors
Drugs			Promethazine
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)	Lymphocyte counts ( 32888494)
Interacting Genes		52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1	5 interacting genes: EMP1 RPRM SEC22A SMIM3 TSC22D1
Entrez ID		85027	10161
HPRD ID		12212	16465
Ensembl ID		ENSG00000256235	ENSG00000139679
Uniprot IDs		Q9BZL3	A0A024RDT2 B3KVQ5 P43657
PDB IDs
Enriched GO Terms of Interacting Partners?
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