PKP4 and MINK1

Number of citations of the paper that reports this interaction (PubMedID 15032605)
1

Data Source:
HPRD (two hybrid)

		PKP4	MINK1
Description		plakophilin 4	misshapen like kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cornified Envelope Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Cell Junction Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Axon Dendrite Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Cell-cell Junction Assembly Cell-cell Signaling Regulation Of Cell Adhesion Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Cell-cell Adhesion	MAPK Cascade Regulation Of Cell-matrix Adhesion Protein Phosphorylation JNK Cascade Chemical Synaptic Transmission Multicellular Organism Development Regulation Of Cell-cell Adhesion Microvillus Assembly Regulation Of Cell Migration Actin Cytoskeleton Reorganization Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Dendrite Morphogenesis Positive Regulation Of P38MAPK Cascade Regulation Of AMPA Receptor Activity
Pathways		Keratinization Formation of the cornified envelope RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	Oxidative Stress Induced Senescence
Drugs			Fostamatinib
Diseases
GWAS		Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)	Intracranial aneurysm ( 30823506) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Metabolite levels (lipid measures) ( 27005778) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) PR interval ( 32439900)
Interacting Genes		22 interacting genes: ARMC8 ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OGT OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 SCN2A TRIM23 UBASH3B	14 interacting genes: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ
Entrez ID		8502	50488
HPRD ID		05043	11366
Ensembl ID		ENSG00000144283	ENSG00000141503
Uniprot IDs		Q99569	Q8N4C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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