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PPFIA1 and CCNH
Number of citations of the paper that reports this interaction (PubMedID
29892012
)
25
Data Source:
BioGRID
(two hybrid)
PPFIA1
CCNH
Description
PTPRF interacting protein alpha 1
cyclin H
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Focal Adhesion
Presynaptic Active Zone
Transcription Factor TFIIH Core Complex
Nucleus
Nucleoplasm
Transcription Factor TFIIH Holo Complex
Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex
CAK-ERCC2 Complex
Transcription Factor TFIIK Complex
Molecular Function
Protein Binding
Protein Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Biological Process
Cell-matrix Adhesion
Signal Transduction
Synapse Organization
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Protein Localization To Plasma Membrane
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Cell Cycle
Protein Stabilization
Phosphorylation Of RNA Polymerase II C-terminal Domain
Pathways
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Receptor-type tyrosine-protein phosphatases
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
)
Lymphocyte counts (
32888494
)
Adult body size (
32376654
)
Bipolar disorder lithium response (continuous) or schizophrenia (
29121268
)
Blood protein levels (
29875488
)
Diastolic blood pressure (
27841878
)
Fasting glucose (
34074324
)
Initial pursuit acceleration (
29064472
)
Macular thickness (
30535121
)
Major depressive disorder (
23377640
)
Prostate cancer aggressiveness (
25939597
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
)
Interacting Genes
31 interacting genes:
AGTPBP1
CAGE1
CAST
CCNH
CDK18
CEP70
DTNB
DYNC1I2
ELOA
ERC1
ERC2
FAM161A
GAS8
GIT1
MBIP
NCOA2
NDN
PPFIA2
PPFIA3
PPFIBP1
PPFIBP2
PPP2R5A
PPP2R5D
PTPRC
PTPRD
PTPRF
PTPRS
SHANK2
TNNT1
TXLNA
YWHAG
48 interacting genes:
AR
BLZF1
CALCOCO2
CCDC170
CCDC33
CCNC
CCT4
CDK2
CDK20
CDK3
CDK6
CDK7
CDK8
CSNK2B
CTBP2
DUSP12
ERCC3
ESR1
FUBP1
GANAB
GOLGA2
GRIPAP1
GTF2E2
GTF2H1
KLC3
MCM7
MCRS1
MTA1
MTMR7
NDC80
NEDD4
PICK1
POLR2A
POLR2B
PPFIA1
PSMA1
RARB
RHOH
SFN
SORBS3
SSX2IP
SUPT5H
TCF4
TP53
TRIM8
TRIML2
ZNF655
ZNRD2
Entrez ID
8500
902
HPRD ID
11451
09059
Ensembl ID
ENSG00000131626
ENSG00000134480
Uniprot IDs
B3KVS8
Q13136
P51946
PDB IDs
1N7F
1JKW
1KXU
6O9L
6XBZ
6XD3
7B5O
7B5Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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