OGT and CSNK2A1

Number of citations of the paper that reports this interaction (PubMedID 10753899)
103

Data Source:
HPRD (in vitro)

		OGT	CSNK2A1
Description		O-linked N-acetylglucosamine (GlcNAc) transferase	casein kinase 2 alpha 1
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Mitochondrial Membrane Protein-containing Complex Cell Projection	Nucleus Nucleoplasm Cytosol Plasma Membrane Protein Kinase CK2 Complex Sin3 Complex NuRD Complex
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Protein O-GlcNAc Transferase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Identical Protein Binding Protein N-terminus Binding Hsp90 Protein Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Glycolytic Process Regulation Of Gluconeogenesis Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Protein Processing Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Regulation Of Necroptotic Process Positive Regulation Of Histone H3-K27 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Cold-induced Thermogenesis	Protein Phosphorylation Apoptotic Process Cell Cycle Signal Transduction Positive Regulation Of Cell Population Proliferation Wnt Signaling Pathway Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Cell Growth Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Protein Catabolic Process Rhythmic Process Regulation Of Cell Cycle Chaperone-mediated Protein Folding Regulation Of Chromosome Separation Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Signaling Pathway
Pathways		HATs acetylate histones RIPK1-mediated regulated necrosis Regulation of necroptotic cell death UCH proteinases	Synthesis of PC WNT mediated activation of DVL Condensation of Prometaphase Chromosomes Signal transduction by L1 Regulation of TP53 Activity through Phosphorylation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding ROS sensing by NFE2L2 Receptor Mediated Mitophagy RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN stability and activity
Drugs			ATP (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One Resveratrol 1,8-Di-Hydroxy-4-Nitro-Anthraquinone Benzamidine 5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone Quercetin Phosphoaminophosphonic Acid-Adenylate Ester Tetrabromo-2-Benzotriazole DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE Emodin 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE Dichlororibofuranosylbenzimidazole Quinalizarin Ellagic acid Fostamatinib
Diseases
GWAS		Red cell distribution width ( 32888494)	Night sleep phenotypes ( 27126917) Pursuit maintenance gain ( 29064472)
Interacting Genes		725 interacting genes: - AAMP AARSD1 AASS ABI1 ABI2 ABRAXAS1 ABRAXAS2 ACOX1 ACTB ACTC1 ACTL6A ACTR3 ADPGK ADSL AGFG1 AHSA1 ALDH1A2 ALDH1B1 ALDH2 ALDH4A1 ALDH5A1 ALDH6A1 ALDH7A1 ALDOA ALKBH5 ANAPC7 ANXA11 ANXA6 ANXA7 API5 APMAP APOH ARHGAP1 ARHGAP19 ARIH2 ARMC6 ASCC1 ASPH ATAD3A ATG5 ATIC ATL2 ATL3 ATP1B1 ATP1B3 ATP5F1A ATP5F1B ATP6AP1 ATXN10 ATXN2L B3GLCT B4GAT1 BAG1 BAIAP2 BCCIP BCLAF1 BEND7 BIRC5 BSG BYSL BZW2 C17orf75 CAAP1 CALR CARS2 CASP8 CAT CAVIN1 CBLL1 CBR1 CBWD6 CCDC47 CCDC77 CCDC86 CCNB1 CCT2 CCT3 CCT4 CCT5 CCT6A CCT7 CCT8 CD2BP2 CDC123 CDC37 CDC42EP1 CDC5L CDC6 CDK9 CDKAL1 CELF1 CENPU CEP43 CEP55 CEP57 CHMP7 CHST7 CIR1 CKAP4 CKB CKMT1A CLCC1 CLN5 CLPB CLPX CNDP2 CNOT11 COIL COPS2 COQ8B CPSF6 CPSF7 CREBBP CRTAP CSNK1G2 CSNK2A1 CSNK2B CTNND1 CTSD CTU2 CWC25 CWC27 CXADR DAPK3 DAZAP1 DBN1 DBNL DBT DCTN2 DDX17 DDX28 DDX39B DDX3X DDX41 DDX47 DDX5 DDX56 DEK DHX30 DHX9 DLD DLG3 DLST DMAP1 DNAJA1 DNAJA2 DNAJC3 DNAJC7 DUS1L DYNC1LI1 DYNC1LI2 EARS2 ECSIT EDC3 EEF1A1 EEF1G EHD1 EIF2AK2 EIF2S2 EIF3D EIF3E EIF3F EIF3G EIF4A1 EIF4G2 EIF5 ELOA ENO1 ERGIC3 ERI1 ERO1A ERO1B ESS2 ETF1 EWSR1 FAF2 FAM199X FAM98A FARSA FDXR FEN1 FH FIP1L1 FIZ1 FKBP10 FKBP4 FKBP5 FKBP8 FNTA FTO FTSJ3 FUBP3 FUCA1 FUCA2 FUS G3BP1 G3BP2 GABPA GAPDH GART GATA6 GATB GBA GDI1 GDI2 GLA GLB1 GLMN GLS GLUD1 GNL3 GORASP2 GPATCH4 GPKOW GPS1 GPT2 GRSF1 GRWD1 GSK3A GSK3B GSS GSTM3 GSTP1 GTF2E1 GTF2H1 GTF3C5 GTPBP3 GXYLT1 H1-4 HABP4 HARS1 HARS2 HAUS8 HCFC1 HDAC1 HGH1 HIRA HIVEP1 HMGCS1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HP1BP3 HS2ST1 HSP90AA1 HSP90AB1 HSP90B1 HSPA13 HSPA14 HSPA1A HSPA5 HSPA8 HSPA9 HSPD1 IFRD2 IGF2BP1 IGF2BP2 IGF2BP3 IGKV2D-29 IK IKBIP ILF2 ILF3 ILK ILKAP IMPDH1 IMPDH2 IPO5 IRF3 IRS4 IST1 ISYNA1 JMJD6 KARS1 KATNA1 KHDRBS1 KHDRBS3 KNOP1 KPNA1 KPNA2 KPNA3 KPNA4 KPNA6 KPNB1 KRR1 KRT1 KRT10 KRT2 KRT8 KRT9 LACTB LAP3 LARP4B LDHB LEMD2 LENG9 LETM1 LMAN1 LMNA LNPK LPCAT1 LPCAT4 LRP4 LRRFIP2 LSM14A LSM14B LSR LTV1 LUC7L2 LUC7L3 LYAR MAP1A MAP7D1 MAPT MARS2 MAT2A MAZ MCCC2 ME1 ME2 MEAK7 METAP2 MFAP1 MICU1 MINPP1 MPP1 MRM3 MSTO1 MTDH MYEF2 NAE1 NAMPT NAP1L1 NAP1L4 NASP NCL NDUFV1 NELFCD NISCH NKAP NOC4L NOLC1 NOM1 NONO NOP53 NOP58 NPM1 NSMCE4A NSUN5 NSUN6 NT5DC1 NUDC NUF2 NUFIP1 NUFIP2 NUP50 NUP54 NUP62 NUP62CL NUSAP1 NXN OAT OCLN OGA OLA1 OXCT1 OXSR1 P3H4 P4HA1 P4HA2 P4HB PA2G4 PABPC1 PABPC4 PABPN1 PACSIN3 PAIP1 PAK2 PALS2 PARD6B PARP1 PARVA PCBP1 PCBP2 PCGF2 PCGF6 PCYOX1 PDCD2L PDCD4 PDCD7 PDHX PDIA3 PDIA5 PDIA6 PDP1 PEX14 PGD PGK1 PGM1 PHAX PHC3 PHF10 PHF6 PHGDH PI4K2A PICALM PIP4K2C PKM PKP4 PLD3 PLEKHO1 PLIN2 PLS3 PM20D2 PMPCA PNKP PNMA8A POGLUT3 POLD2 POLDIP3 POLM POLR1E POLR3C POLR3D POMK PPAT PPHLN1 PPM1F PPP1R7 PPP2R1A PPP2R1B PPP2R5C PPP2R5E PPP3CA PPP5C PRC1 PRCP PRIM1 PRIM2 PRKAR1A PRKAR2A PRKAR2B PRORP PRPF19 PRPF31 PRRC1 PSG1 PSIP1 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD12 PSMD4 PSPC1 PTBP1 PTBP2 PUF60 PURA PWP1 QRSL1 RAB11FIP2 RAD23A RAD23B RANGAP1 RAP1GDS1 RARS1 RARS2 RBBP4 RBBP7 RBFOX2 RBM14 RBM17 RBM22 RBM23 RBM39 RBM42 RBM45 RBMS1 RBMX RCC1 RCN2 REPIN1 REXO4 RIC8A RING1 RIOX2 RNH1 RNPS1 RO60 RPL10 RPL10A RPL11 RPL12 RPL13 RPL22 RPL24 RPL3 RPL30 RPL4 RPL5 RPL6 RPL7 RPL8 RPL9 RPLP0 RPS2 RPS24 RPS3 RPS3A RPS4X RPS7 RPSA RRP1 RRP1B RRP8 RRS1 RSRC2 RTCB RTN4 RUVBL1 RUVBL2 SAAL1 SAP30BP SARS1 SARS2 SCAI SCLY SCP2 SCRIB SCRN1 SDE2 SEC62 SENP2 SEPTIN11 SEPTIN7 SERBP1 SERPINH1 SETD7 SF1 SF3A2 SF3A3 SF3B4 SFPQ SGSH SH3GLB2 SHMT2 SHOC2 SIN3A SLC9A3R1 SLIT2 SMARCD1 SMARCD2 SMARCE1 SMPDL3B SNAP91 SNRNP70 SNW1 SNX4 SNX5 SNX6 SP1 SPAST SPATS2 SPATS2L SPOUT1 SQSTM1 SRF SRFBP1 SRP54 SRP68 SRP72 SRSF11 SRSF6 SRSF7 SSB ST13 STAU1 STAU2 STIP1 STK24 STK25 STK26 STK3 STK4 STOML2 SYAP1 SYNCRIP TAB1 TAB3 TADA2B TADA3 TAF15 TAF7 TARBP2 TBCE TBCEL TBL1XR1 TCP1 TCP11L1 TEDC1 TEDC2 TENT2 TERF1 TET2 TFDP1 TFG THAP11 THRAP3 THUMPD1 TMCC3 TMEM30A TMPO TMX3 TOE1 TOM1 TOMM70 TOR1AIP1 TOR1AIP2 TP53 TPP1 TRAF4 TRAF7 TRAK1 TRAK2 TRIM11 TRIM27 TRIM28 TRIP12 TRIT1 TRMT10C TRMT5 TRMT6 TSG101 TSPYL1 TTC31 TTC4 TUBA1A TUBA1B TUBA1C TUBA4A TUBB TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBG1 TUFM TXNDC5 U2AF2 UBA1 UBA3 UBA5 UBC UBE2Q1 UBR7 UBXN6 UCHL5 UMPS UPF3B UQCRC1 USP14 UTP18 UTP3 VEZF1 VIM VIPAS39 VPS4A VPS4B VRK1 VRK2 VRK3 WARS1 WBP4 WDR55 WT1 WTAP XIAP XPO1 XRCC4 XRCC6 XRN2 YARS1 YBX1 YBX3 YES1 YJU2B YME1L1 YTHDF2 ZC3H15 ZC3HAV1 ZCCHC3 ZKSCAN4 ZKSCAN8 ZNF124 ZNF207 ZNF277 ZNF385A ZNF397 ZNF436 ZNF460 ZNF48 ZNF622 ZNF70 ZNF703 ZNF768 ZNF787 ZNHIT2 ZPR1 ZRANB2 ZSCAN21	436 interacting genes: - ABCA1 ABCC1 ACACA ACAT2 ACE ACIN1 AIP AKAP8 AKT1 ALKBH5 ANP32B APEX1 APOE APP AQP4 ARL6IP4 ARMCX3 ARNT ARR3 ARRB2 ASIC3 ATF1 ATF2 ATG16L1 ATN1 ATP2B1 ATP5F1A AUTS2 BCLAF1 BDP1 BEND7 BHLHE41 BID BIRC6 BMS1 BRCA1 BRF1 BRMS1 C1orf109 C1orf35 C1R CALM1 CALU CANX CARD9 CASP2 CASQ2 CAV1 CAV2 CCDC116 CCDC6 CD2BP2 CD5 CDC25B CDC37 CDH1 CDK1 CDKN1A CFDP1 CHD4 CHUK CIRBP CLASP2 CLNS1A CLTB COPS2 COPS3 COPS7A CPSF6 CPSF7 CREB3L3 CREBBP CREM CSN1S1 CSN2 CSNK2B CT45A1 CTDP1 CTNNA1 CTNNB1 CUX2 DAXX DDIT3 DDX17 DDX21 DDX24 DDX3X DDX54 DEK DELEC1 DHX16 DHX38 DKC1 DNAJB2 DPF3 DTD1 DVL1 DVL3 ECD EEF1B2 EEF1D EGR1 EHMT2 EIF2B5 EIF2S1 EIF2S2 EIF3J EIF4B EIF4EBP1 EIF5 EIF5B ERH EXOSC9 F11R F5 FAF1 FAM133A FBXO28 FCHO1 FGF1 FGF2 FIBP FIP1L1 FKBP3 FKBP4 FLG FNBP4 FOS FTSJ3 FXR1 GABRR1 GABRR2 GANAB GAP43 GGA1 GMFB GMNN GPATCH2 GPATCH2L GPI GPN1 GRIN2A GRIN2B GSC2 GTF2A1 GTF2A1L GTF2F1 GYS1 HCLS1 HDAC1 HDAC2 HDAC3 HDGFL2 HDLBP HES6 HGS HIF1A HMGA1 HMGA2 HMOX2 HNRNPA2B1 HNRNPC HNRNPDL HNRNPL HOXB7 HOXC4 HSF1 HSP90AA1 HSP90AB1 HSP90B1 HSPA4 HSPB8 HSPH1 HTATSF1 IFI16 IFRD1 IGF2R IGFBP3 IL16 INF2 IRF2 IRS1 ITCH IWS1 JADE2 JUN KANK2 KDM1A KEAP1 KIF1C KIF24 KIF5C KLF1 KPNA4 L1CAM LARP1 LEO1 LGALS3 LHX3 LHX8 LHX9 LIG1 LRRC59 LSM14A LTV1 MAF1 MAGEA11 MAK16 MAPK1 MAPK14 MAPT MAX MAZ MCM2 MCM3 MDC1 MDM2 MEF2C MEOX1 MEOX2 MFAP1 MGMT MME MPHOSPH10 MRPL38 MRPL4 MS4A1 MSH6 MTDH MUS81 MYB MYC MYCN MYF5 MYH9 NAF1 NAP1L1 NAP1L4 NCAPD2 NCL NCOR1 NFKBIA NFKBIB NFYA NKX2-5 NMD3 NMT1 NOL3 NOLC1 NOP56 NOP58 NPM1 NRF1 NUP98 NXF1 OCLN OGDHL OGT OSBP OTUB1 PACS1 PAFAH1B1 PAK1 PAX5 PAX6 PAX7 PDAP1 PDCD4 PDIA6 PGK1 PGR PHF19 PIAS1 PIN1 PIN4 PIP4K2B PLEKHO1 PML PNN POLR2A POU6F2 PPAN PPP1R1B PPP1R2 PPP1R8 PRCC PRKACB PRNP PRPF38A PSEN2 PSIP1 PSMA3 PSMA4 PSME3IP1 PTEN PTPA PTPN1 PTPRC PURB RAD1 RAD51 RAD9A RANGAP1 RBM10 RBM17 RBM33 RBM39 RBMX REL RELA RGS19 RIOK1 RIOK2 RNF111 RNF7 RPL13 RPL5 RPL6 RPLP0 RPLP1 RPRD2 RPS18 RPS3 RPS6KB1 RRAD RRP12 RRP1B RRP9 RSF1 RSL1D1 SAFB SAP30BP SAT1 SCNN1A SEPTIN2 SERBP1 SERPINF1 SF3A1 SF3B1 SF3B2 SFPQ SHOX SLC18A2 SLC4A1AP SLIRP SMARCC2 SNAI2 SNCA SND1 SP1 SPATS2L SPI1 SPIB SPP1 SPTBN1 SQSTM1 SREK1 SRF SRRM1 SRRM2 SRRT SRSF10 SRSF11 SRSF2 SSB SSRP1 STAC3 STMN1 STX1A SUB1 SUDS3 SUGT1 SUPT5H SUPT6H SURF6 TCF7L2 TCOF1 TEPSIN TFAP2A TH THAP1 THOC5 THRAP3 TLE5 TMOD3 TMPO TNKS1BP1 TNP1 TOP1 TOP2A TP53 TP63 TP73 TRIM41 TSPY1 TSPYL2 UBAC1 UBE2D3 UBE2R2 UBTF USP24 USP48 USP7 UTP14A UTP18 VAMP4 VDR VHL VTN WAS WDR44 WDR55 WEE1 XK XKRY XRCC1 XRCC4 XRCC5 XRCC6 XRN2 YBX1 YWHAB YWHAQ ZC3H13 ZC3H15 ZC3H8 ZFC3H1 ZHX1 ZNF177 ZNF440 ZNF558 ZNF559-ZNF177 ZNF670 ZRANB2 ZSCAN25
Entrez ID		8473	1457
HPRD ID		02222	00277
Ensembl ID		ENSG00000147162	ENSG00000101266
Uniprot IDs		O15294	P68400
PDB IDs		1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4CDR 4GYW 4GYY 4GZ3 4GZ5 4GZ6 4N39 4N3A 4N3B 4N3C 4XI9 4XIF 5BNW 5C1D 5HGV 5LVV 5LWV 5NPR 5NPS 5VIE 5VIF 6E37 6EOU 6IBO 6MA1 6MA2 6MA3 6MA4 6MA5 6Q4M 6TKA	1JWH 1NA7 1PJK 2PVR 2ZJW 3AMY 3AT2 3AT3 3AT4 3AXW 3BQC 3C13 3FWQ 3H30 3JUH 3MB6 3MB7 3NGA 3NSZ 3OWJ 3OWK 3OWL 3PE1 3PE2 3PE4 3Q04 3Q9W 3Q9X 3Q9Y 3Q9Z 3QA0 3R0T 3RPS 3TAX 3U4U 3U87 3U9C 3W8L 3WAR 3WIK 3WIL 3WOW 4DGL 4FBX 4GRB 4GUB 4GYW 4GYY 4GZ3 4IB5 4KWP 4MD7 4MD8 4MD9 4NH1 4RLL 4UB7 4UBA 5B0X 5CLP 5CQU 5CQW 5CS6 5CSH 5CSP 5CSV 5CT0 5CTP 5CU0 5CU2 5CU3 5CU4 5CU6 5CVF 5CVG 5CVH 5CX9 5H8B 5H8E 5H8G 5HGV 5KU8 5KWH 5M44 5M4C 5M4F 5M4I 5MMF 5MMR 5MO5 5MO6 5MO7 5MO8 5MOD 5MOE 5MOH 5MOT 5MOV 5MOW 5MP8 5MPJ 5N1V 5N9K 5N9L 5N9N 5NQC 5OMY 5ONI 5OQU 5ORH 5ORJ 5ORK 5OS7 5OS8 5OSL 5OSP 5OSR 5OSU 5OSZ 5OT5 5OT6 5OTD 5OTH 5OTI 5OTL 5OTO 5OTP 5OTQ 5OTR 5OTS 5OTY 5OTZ 5OUE 5OUL 5OUM 5OUU 5OWH 5OWL 5OYF 5T1H 5VIE 5VIF 5ZN0 5ZN1 5ZN2 5ZN3 5ZN4 5ZN5 6A1C 6E37 6EHK 6EHU 6EII 6FVF 6FVG 6GIH 6GMD 6HBN 6HME 6HNW 6HNY 6HOP 6HOQ 6HOR 6HOT 6HOU 6JWA 6L1Z 6L21 6L22 6L24 6Q38 6Q4Q 6QY7 6RB1 6RCB 6RCM 6RFE 6RFF 6SPW 6SPX 6TEI 6TLL 6TLO 6TLP 6TLR 6TLS 6TLU 6TLV 6TLW 6YPG 6YPH 6YPJ 6YPK 6YPN 6YUL 6YUM 6Z83 6Z84 7A49 7A4B 7A4C 7B8H 7B8I
Enriched GO Terms of Interacting Partners?
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