GTPBP3 and DPPA4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		GTPBP3	DPPA4
Description		GTP binding protein 3, mitochondrial	developmental pluripotency associated 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Nucleus Nucleoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Chromatin Binding Protein Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Methylation	System Development Lung-associated Mesenchyme Development
Pathways		tRNA modification in the mitochondrion	POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525)	Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774	35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM
Entrez ID		84705	55211
HPRD ID		12255	16836
Ensembl ID		ENSG00000130299	ENSG00000121570
Uniprot IDs		B7Z563 Q969Y2	Q7L190
PDB IDs
Enriched GO Terms of Interacting Partners?
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