SMARCA5 and POLE3

Number of citations of the paper that reports this interaction (PubMedID 26344197)
178

Data Source:
BioGRID (biochemical, pull down)

		SMARCA5	POLE3
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	DNA polymerase epsilon 3, accessory subunit
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Cytosol NURF Complex RSF Complex Intracellular Membrane-bounded Organelle Nuclear Replication Fork	Nucleus Nucleoplasm Epsilon DNA Polymerase Complex CHRAC
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Hydrolase Activity ATP Hydrolysis Activity Nucleosome Binding Histone Binding ATP-dependent Chromatin Remodeler Activity	DNA-directed DNA Polymerase Activity Protein Binding Chromatin DNA Binding Protein Heterodimerization Activity
	Biological Process	RDNA Heterochromatin Assembly Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor	DNA Replication Leading Strand Elongation Cellular Response To DNA Damage Stimulus Heterochromatin Assembly Nucleosome Mobilization Histone H3 Acetylation DNA Biosynthetic Process
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere	Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs		Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose	Cladribine
Diseases
GWAS		Height ( 31562340) Malaria ( 31844061)
Interacting Genes		19 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B GSK3A H3-3A H3C1 H4-16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1	14 interacting genes: ALAD APP ASTN2 BAZ1A CHRAC1 CST3 DR1 DRAP1 EIF4G2 GSN POLE4 SMARCA5 TNC TRIM32
Entrez ID		8467	54107
HPRD ID		04538	06274
Ensembl ID		ENSG00000153147	ENSG00000148229
Uniprot IDs		O60264	A0A024R829 Q9NRF9
PDB IDs		6NE3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?