ATRN and XRN2

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		ATRN	XRN2
Description		attractin	5'-3' exoribonuclease 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Basement Membrane Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Membrane Aggresome
	Molecular Function	Carbohydrate Binding Signaling Receptor Activity	3'-5'-exoribonuclease Activity Transcription Termination Site Sequence-specific DNA Binding RNA Binding Nuclease Activity 5'-3' Exoribonuclease Activity Protein Binding 5'-3' Exonuclease Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Inflammatory Response Response To Oxidative Stress Animal Organ Morphogenesis Tissue Development Cell Migration Cerebellum Development Substrate Adhesion-dependent Cell Spreading Regulation Of Multicellular Organism Growth Myelination Pigmentation	DNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process DNA-templated Transcription, Termination RRNA Processing RNA Processing MRNA Processing RNA Catabolic Process Spermatogenesis RNA Metabolic Process Hippocampus Development Neuron Differentiation Retina Development In Camera-type Eye RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways			Association of TriC/CCT with target proteins during biosynthesis Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Asthma ( 29273806) Diisocyanate-induced asthma ( 25918132) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte count ( 32888494) Night sleep phenotypes ( 27126917) Postcentral gyrus volume ( 31530798) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Autism spectrum disorder ( 30804558) Hip circumference adjusted for BMI ( 34021172) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		3 interacting genes: COPS5 XRN2 ZNF408	36 interacting genes: ALDH1B1 ATRN BFSP1 COMT CRY2 CSNK2A1 CTSC DXO DYNLT1 EEF1A1 EIF3L EIF5A EIF6 ERG EXOSC10 EXOSC8 LCN2 LSM3 MAGEA11 MOCS3 MRPL4 MRPS10 OGT PGM1 PLEKHF2 PRAME PSMA3 PYGB RAB14 SETMAR STK39 TARDBP TIPARP TOLLIP TTC23 UPF2
Entrez ID		8455	22803
HPRD ID		04388	10309
Ensembl ID		ENSG00000088812	ENSG00000088930
Uniprot IDs		B4DZ36 O75882	B4DZC3 Q9H0D6
PDB IDs
Enriched GO Terms of Interacting Partners?
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