MON1A and RABGEF1

Number of citations of the paper that reports this interaction (PubMedID 20434987)
260

Data Source:
BioGRID (pull down)

		MON1A	RABGEF1
Description		MON1 homolog A, secretory trafficking associated	RAB guanine nucleotide exchange factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Mon1-Ccz1 Complex	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	DNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding
	Biological Process	Protein Targeting To Vacuole Protein Secretion Vesicle-mediated Transport Regulation Of Catalytic Activity	Protein Targeting To Membrane Endocytosis Regulation Of Catalytic Activity
Pathways		RAB GEFs exchange GTP for GDP on RABs	TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Body mass index ( 28892062 25673413 29273807) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)	Aortic root size ( 21223598) Central corneal thickness ( 32528159 29760442)
Interacting Genes		7 interacting genes: FYCO1 GFI1B MAPK6 RABGEF1 RGS2 TAB1 VPS33A	50 interacting genes: ABI2 ANKRD29 AP1G1 ARRDC3 BLOC1S6 CCHCR1 CDC37 CIPC DAZAP2 DCTN2 DGCR6 DNAJC5 EMILIN1 GGA1 GGA2 GPRASP2 HOOK2 HRAS IHO1 KXD1 MID2 MON1A MON1B OIP5 RAB33B RAB4A RABEP1 RAD23A RASAL3 RNF11 RNF168 RPS27A SESTD1 SNAPIN SPART SSX3 TCHP TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBA52 UBB UBC UBE2D1 UBE2D3 WASHC1 YWHAB ZC2HC1C
Entrez ID		84315	27342
HPRD ID		17586	11477
Ensembl ID		ENSG00000164077	ENSG00000154710
Uniprot IDs		Q86VX9	A0A024RDL6 A8K3R3 B3KMF1 Q9UJ41
PDB IDs			1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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