CASP10 and DEDD

Number of citations of the paper that reports this interaction (PubMedID 12527898)
24

Data Source:
HPRD (in vitro)

		CASP10	DEDD
Description		caspase 10	death effector domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol CD95 Death-inducing Signaling Complex Ripoptosome	Nucleolus Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Ubiquitin Protein Ligase Binding Death Effector Domain Binding Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis	DNA Binding Protein Binding
	Biological Process	Proteolysis Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apoptotic Signaling Pathway Execution Phase Of Apoptosis	Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways		TP53 Regulates Transcription of Caspase Activators and Caspases FasL/ CD95L signaling TRAIL signaling NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Basal cell carcinoma ( 25855136) Chronic lymphocytic leukemia ( 28165464 23770605) Chronic lymphocytic leukemia or rheumatoid arthritis ( 31407831) Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		36 interacting genes: BFAR BID BMPR2 CASP1 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8 CASP8AP2 CASP9 CCAR1 CFLAR DEDD DEDD2 DSP ECE2 ERBB4 FADD IGFBP2 NFKBIL1 NPTX1 OIP5 PHF20L1 POLR2A PRDX6 RB1 RIOK3 RYBP SCARB1 TNFRSF1A TRAF1 XIAP YBX3	24 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 IRF9 KRT18 KRT8 MPZ NR1I3 PRRC2C SDHC SHMT1 SLC19A2 SMAD3 UAP1 VPS26A
Entrez ID		843	9191
HPRD ID		03458	06022
Ensembl ID		ENSG00000003400	ENSG00000158796
Uniprot IDs		A0A0S2Z3G5 A0A0S2Z3Z5 Q92851	B1AQP5 O75618
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?