CAPNS2 and PHACTR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		CAPNS2	PHACTR3
Description		calpain small subunit 2	phosphatase and actin regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleoplasm Nuclear Matrix
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding
	Biological Process	Proteolysis	Actin Cytoskeleton Organization Negative Regulation Of Catalytic Activity
Pathways		Degradation of the extracellular matrix Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
Diseases
GWAS		Thyroid hormone levels ( 23408906)	Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Refractive error ( 32231278) Rheumatoid arthritis ( 30891314) Schizophrenia ( 30285260)
Interacting Genes		9 interacting genes: APP ARMC10 CAPN2 CMTM5 OXNAD1 PHACTR3 PPIC PRPF31 RIN1	10 interacting genes: CAPNS2 CYB5B EEF1G MAPK6 PLPP6 PPP1CA PPP1CB TAB1 UBIAD1 UBL5
Entrez ID		84290	116154
HPRD ID		16682	10571
Ensembl ID		ENSG00000256812	ENSG00000087495
Uniprot IDs		Q96L46	B7Z339 Q96KR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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