CIAO2A and SETD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CIAO2A	SETD4
Description		cytosolic iron-sulfur assembly component 2A	SET domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol CIA Complex	Nucleus Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	Protein-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific) Histone Methyltransferase Activity (H3-K4 Specific)
	Biological Process	Chromosome Segregation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer Protein Maturation By [4Fe-4S] Cluster Transfer	Inflammatory Response Peptidyl-lysine Trimethylation Peptidyl-lysine Monomethylation Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Histone H4-K20 Trimethylation Histone H3-K4 Dimethylation Positive Regulation Of Inflammatory Response Regulation Of Cell Proliferation In Bone Marrow Histone H3-K4 Monomethylation
Pathways
Drugs
Diseases
GWAS			Asthma (adult onset) ( 31036433) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Obesity-related traits ( 23251661)
Interacting Genes		25 interacting genes: AGTRAP APOA2 CIAO1 CMTM6 CREB3L1 DERL1 DGAT2L6 EBAG9 ERGIC3 FKBP7 GJA8 GSC2 KCNIP1 LIME1 MEST PLP2 PLPP6 PLPPR2 PRAF2 RHBDD2 SETD4 SIN3A TMED8 TNFRSF10D VAMP3	3 interacting genes: CHAF1B CIAO2A MORC3
Entrez ID		84191	54093
HPRD ID		08010	10743
Ensembl ID		ENSG00000166797	ENSG00000185917
Uniprot IDs		Q9H5X1	A8MTS1 Q9NVD3
PDB IDs		2M5H 3UX2 3UX3
Enriched GO Terms of Interacting Partners?
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